What Are The Four Stages of Mesothelioma Cancer?

One rare form of cancer is called Mesothelioma, a malignant tumor in the mesothelial tissues of the lungs and the abdomen, arising from the inhalation of asbestos. Its rarity is one of the reasons why a lot of people are not aware of this kind of fatal disease. In fact, many people die of Mesothelioma undiagnosed. Although there is now a growing awareness of the hazards of asbestos to health, still many have not heard of Mesothelioma and thus, have not understood its nature, cause, signs and treatment. Even some physicians find it hard to detect Mesothelioma because its symptoms are akin to other diseases like lung cancer and pneumonia. Furthermore, it takes decades for a patient who was exposed to asbestos to develop Mesothelioma — fifty years, at most.

Being unaware of Mesothelioma poses higher risks since it deters diagnosis and treatment. A person undergoing treatment must know the different stages of the cancer or the extent of the disease. Chances of recovering from Mesothelioma and the kind of treatment depend on the stage of the illness. There are basically two staging systems used for Pleural Mesothelioma (lungs): TNM system and Brighan system. These staging systems are also used in other kinds of cancers; however, the first is commonly used. There is no established method in determining the stage of the Peritoneal Mesothelioma cancer (abdominal) so the TNM system is used.


There are three variables in the TNM system: tumor, lymph nodes and metastasis. In the earliest stage of Mesothelioma, stage I, the malignant Mesothelioma cells start to grow and multiply only one layer of the pleura. The pleura is the membrane that encloses the lungs and lines the wall of the chest cavity. However, there are some instances wherein the pericardium (membrane that covers the heart) and diaphragm cover are already affected. In this case, the cancer patient is still in stage I Mesothelioma.

In the second stage, the two layers of the pleura are already affected by Mesothelioma. Take note, however, that in this stage, only one side of the body is affected. Normally, the pleura produces only small amount of lubricating fluid that allows easy expanding and contracting of the lungs. The excess fluid is absorbed by the blood and the lymph vessels so there’s a balance between the amount of fluid produced and removed. During the second stage Mesothelioma, fluid starts to build up between the membrane of the lungs and the membrane of the chest wall, resulting to pleural effusion. The increase in the volume of fluid produced causes shortness of breath and chest pain. Other Mesothelioma cancer patients experience dry and persistent cough. Diagnosis of the pleural effusion is achieved through a chest x-ray.

Stage III Mesothelioma means that the malignant cells have already spread to the chest wall, esophagus and the lymph nodes on one part of the chest. The patient may suffer severe pain near the parts affected. When not treated immediately or when the Mesothelioma patient doesn’t respond well to medication, the cancer may advance to the fourth stage. The fourth stage Mesothelioma is formidable since at this stage the Mesothelioma cells have penetrated into the bloodstream and other organs in the body like the liver, the bones and the brain. The lymph nodes on the other side of the chest may also be affected by Mesothelioma in stage IV.

Brighan staging system, on the other hand, determines whether the Mesothelioma can be surgically removed or not and whether the lymph nodes are affected or not. In stage I Mesothelioma, the lymph nodes are not yet affected and the patient can still recover through surgery. In stage II, surgery can still be executed but some lymph nodes have already been infiltrated by the cancer cells. In stage III, the heart and chest wall are already affected; thus, surgery is no longer advisable. The lymph nodes in this stage, however, may or may not be affected. In the final stage, stage IV Mesothelioma, cancer cells have already gone to the bloodstream and other parts of the body like the heart, brain, bone and liver. In most cases, a patient who has reached stage IV Mesothelioma only has four to twenty-four months to live.

David Arnold Livingston is a believer in gaining knowledge around Health issues and recommends, as a resource: http://www.newmesothelioma.com/Mesothelioma

By David Arnold Livingston

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Learn How To Prevent Lung Cancer

Lung cancer is a malignant disease commonly associated with people who smoke heavily. It is estimated that a higher number of men are suffering from this form of cancer. Lately however, the number of women affected with lung cancer is steadily catching up with the number of men affected with the disease.

Diet is an important measure in preventing lung cancer. The risk of developing lung cancer for smokers and non-smokers alike are lowered when they eat at least five servings of fruits and vegetables daily. Among the most important fruits and vegetables that should be included in your diet are apples, tomatoes, melons, mangoes, dark leafy greens and onions. Apple and onion are rich in cancer-fighting flavonoids. According to a study conducted in Finland, people who consume more apples are 58 percent less likely to develop lung cancer than those who do not eat apples at all.

Try to add some tomato sauce in your cooking. Research shows that tomatoes, especially cooked ones, seem to exhibit protective properties against lung cancer.



Taking in high amounts of beta-carotenes can also lower the risk of lung cancer in smokers. Carotenoid compounds are found in certain produce like peaches, mangoes, melon, squash, sweet potatoes, pumpkins and green leafy vegetables. Beta-carotene supplement however should be avoided. A study conducted by a Finnish group indicated that an 18 percent rise in lung cancer cases was seen in heavy smokers who were taking beta-carotene supplements. Moreover, the National Cancer Institute researchers also stopped their study on the effects of vitamin A and beta-carotene after smokers who were taking the supplements showed 28 percent more lung cancer than those taking placebos.

Another important measure in the prevention of lung cancer is a routine medical check-up. This should also be accompanied with prophylactic medicines and supplements. An x-ray is necessary especially for those people who smoke and are at the age of 50 and above. A yearly chest x-ray will be especially beneficial for those people who are at high risk of developing lung cancer. A chest x-ray is a preventive measure done to screen for lung cancer. A routine chest x-ray will enable doctors to diagnose lung cancer early so that proper treatment procedures will be implemented.

Aspirin has been shown to ward off lung cancer especially when a dosage of 81 to 325 mg is taken daily. However, you should consult your doctor about the prophylactic advantage of taking aspirin since this form of therapy comes with known side effects.

Selenium that is often found in multivitamin and mineral supplements also shows properties that ward off cancer especially when taken over a long period of time. Some studies show that those who are taking selenium supplements exhibit about 46 percent lower lung cancer rate.

Vitamin C is also good in the prevention of lung cancer. Some studies suggest that people who regularly take 140 mg or more of vitamin C have lower risk of developing lung cancer than those who only get 90 mg or less of vitamin C dosage.

Lifestyle change is also vital in the prevention of lung cancer. People who smoke should consider quitting the habit. When a person stops smoking, his lung cancer risk is lowered by almost half in 10 years.

Finally, the second most common cause of lung cancer is exposure to radon, a colorless gas found in the ground. Test your home for any presence of radon. You can either buy a do-it yourself kit to check for radon which is available in your home supply stores or you can hire a professional to do it for you.

Michael Russell

Your Independent guide to Lung Cancer


By Michael Russell

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Lung Cancer and Smoking

According to the American Cancer Society, today, lung cancer is the leading cause of cancer-related deaths in women. In 2006, an estimated 162,460 deaths resulted from lung cancer, and of those deaths, an estimated 79,560 of those were women. At first glance, the numbers might not seem so alarming., but what is alarming is the fact that "between 1960 and 1990, deaths from lung cancer among women increased by more than 400%" (www.lungcancer.org). Do you need a moment to digest those statistics? I know I did.

In addition, to being the leading cause of cancer-related death for women, the National Cancer Institutes reports that the expected 5-year survival rate for all patients in whom lung cancer is diagnosed is 15.5 percent compared to 64.8 percent for colon, 89 percent for breast and 99.9 percent for prostate cancer. Further, about 6 out of 10 people with lung cancer die within 1 year of being diagnosed with the disease (Lungusa).



After reading the data, I did some research to uncover the cause of such high incidences of lung cancer overall, and particularly, in women. Studies show that while lung cancer can be caused by a variety of factors, including asbestos and environmental pollution, smoking is the leading cause of lung cancer in the United States, with an estimated 90 percent of lung cancer cases caused by smoking. 5 What that means, is that 90 percent of lung cancer cases are preventable; and in 2006, of the 79,560 women that died, 71,685 of those deaths were senseless.

To make the numbers understandable from a layman's point of view, what they correlate to is this: more people have died from smoking in one year than there were American military casualties in Iraq since the war started in 2003, and more than were murdered in the United States in 2005.

Hence, it begs to be considered that if lung cancer is preventable, why do over 1.1 billion people, over 1/6 of the world's total population choose to smoke and ingest harmful tobacco products? This includes 33% of the African population; 57% of the people in the United States; 72% of Europeans; 48% of Southeast Asians, 39% of Eastern Mediterraneans; and 68% of people in Western Pacific nations (World Heath Organization, 2000 estimates).

The answer in short is addiction.

With this in mind, I struck out to learn more about the history of the cigarette. I was in for quite an education. Besides providing you with a history of the cigarette, this article will also educate you on what lung cancer does to your body, steps you can take to prevent it, methods of screening, and resources. Hopefully, what you learn in the following pages will enable you to make a decision that could save a life.

History of the Cigarette
The primary ingredient in a cigarette is tobacco. Tobacco in cigarettes is usually a blend of several types of the tobacco leaf, which have the effect of euphoria on the nervous system. Tar, a by-product of the cigarette, is produced when the cigarette is lit. Nicotine is also part of the make up of the tobacco leaf. When a cigarette is lit and the smoke inhaled, nicotine moves into the blood vessels of the mucous membranes, skin and lungs, and then directly to your brain [within seconds], increasing adrenaline production, stimulating neurons in the brain that cause "good" feelings, which encourage a person to want to repeat the action that caused that feeling (addiction), further stimulating the production and release of endorphins, which cause feelings of euphoria. (howstuffworks.com).

Man has been using the tobacco product for thousands of years. Native Americans smoked prior to the arrival of European explores; and the practice is even depicted in early Mayan art dating back to 1,500 years ago, when tobacco was also used as a medicinal antidote. In the 16th century, smoking was common mostly among sailors. The cigar later became popular in England in the 1820s. The cigarette soon appeared in Spain. During World War I, tobacco products were included in military rations. After the war, manufacturers began advertising cigarette smoking as glamorous, and the rest, as they say is history (Wikipedia).

When manufacturers recognized the marketability of the cigarette, they became interested in learning how to get more people to smoke. Advertising was one way. The other way was to include additives that made cigarette smoking less harsh, more tasty...and more addictive. Today, there are over 599 known additives in cigarettes that have been approved by the United States (U.S.) Government. What most people don't know is that while some of these additives are safe and can be found in everyday foods, others are extremely dangerous when ingested and when burned, these additives produce chemical compounds that are toxic.

Some of the additives included in cigarettes are carbon monoxide, nitrogen oxides, hydrogen cyanide, ammonia, formaldehyde and hydrazine, among others. These harsh chemicals have no natural place in a human body, and even to a layman, it is obvious that these products would be harmful when ingested. Carbon monoxide, for example, a poisonous gas found in car exhaust smoke, when inhaled, can cause fatigue, nausea, disorientation and chest pains. Hydrogen cyanide is used to make fibers, plastics, dyes, pesticides and under the name of Zyklon B, was used as a genocidal agent in World War I. Ammonia is a household cleaner which causes skin, eye, nose, throat and lung irritation. Formaldehyde is used to manufacture building materials and to preserve dead bodies. It causes watery eyes, burning of the eyes, nose and throat, coughing, wheezing and skin irritation. Together with the other additives in a cigarette, each time a smoker lights up and inhales, they are inhaling a "cocktail" of carcinogens, creating a multitude of illnesses in their bodies and speeding up death. At the same time, because the physiological and psychological rewards are so immediate, most smokers, after just one cigarette, are on their way to addiction. Nowadays, cigarettes can be found pretty much everywhere, at neighborhood grocery stores, gas stations, street vendors and even on-line.

Seizing on the lucrative business of addiction, cigarette manufacturers produce approximately 5.5 trillion cigarettes globally each year. China, the United States, Russia, and Japan-the four largest producers-manufacture just over half of the world's supply. In 2004, China produced 1.79 trillion cigarettes, 32 percent of the global total. The United States produced 499 billion, 9 percent of the total. (http://www.worldwatch.org/node/4320)

There are billions of dollars spent every year to target current smokers and recruit new ones. According to the World Health Organization (WHO), major manufacturers like China National Tobacco Company (China), Altria Group, Inc., (previously Phillip Morris Companies) (USA), British American Tobacco PLC (UK), Japan Tobacco (Japan), R J. Reynolds Tobacco (USA), Reemtsman (Germany), Altadis (France and Spain), among others, spend a lot of money to market tobacco. The United States alone spends over $10 billion dollars. This includes promotional funds to retailers to expedite the sales.

This marketing is targeted at adults and youth alike, particularly preying on the naiveté', rebelliousness, experimentive nature of young adults. Cigarette brands like Virginia Slims and Capri's designs appeal to young women, wanting to look more mature, feminine or sexy; and the Joe Camel and the Marlboro man entice young boys who want to look cool, tough and grown up. Cigarette manufacturers went so far as to give cigarettes names that would appeal to younger people. After public outcry from advocacy groups, this year, J. Reynolds Tobacco Co., in particular, agreed to stop using candy, fruit and alcohol names for flavored cigarettes that might appeal to children, The company was using names such as Twista Lime", "Warm Winter Toffee" and "Winter MochaMint.

In the 21st century, the marketing efforts to target youth has evidently stepped up, showing the tenacity of the tobacco manufacturers in retaining what could be their most loyal customers, in spite of over 40 years of opposition from both public and private segments. In the late 1960's, attempts to curb adolescent exposure to cigarette advertising began with the banning of television and radio ads. [However]...the proportion of high school students who smoked rose from 27.5 percent in 1991 to a peak of 36.4 percent in 1997 before drifting back to 28.0 percent in 2000). This increase...was among the factors that prompted a reexamination of regulatory policy, culminating in the November 1998 Master Settlement Agreement (MSA), signed by tobacco manufacturers and forty-six states' attorneys general, prohibits tobacco manufacturers from taking "any action, directly or indirectly, to target Youth within any Settling State in the advertising, promotion or marketing of Tobacco Products." As a blanket youth-targeting ban, this provision applies to all types of advertising, including transit ads, billboards, and magazines (Healthaffairs). Today, in most countries, there are age limit restrictions on the purchase of cigarettes by youth.

As awareness of the health-related disadvantages of smoking and other tobacco products came to the forefront of public consciousness, the public has seen more airing of advertisements, public service announcements, smoking education awareness campaigns, lobbying for smoke free movies and the passing of no-smoking laws in certain building, states and even countries. In countries across the world, like Armenia, Argentina, Australia, Canada, Cuba, France, India, Lithuania, Malaysia, Norway, Singapore, South Africa, Spain and Turkey, smoking is banned in certain public places or workplaces. As always, the cigarette manufacturers are trying to find ways to use even the advertising for non-smoking to their advantage, with large cigarette vendors hiring public relations firms to help them create soft marketing, "non-smoking" ads that would draw in more smokers.

In addition, in order to counter the loss in profits from the bans against smoking and public outcry in the 1980's in the United States and other countries, more aggressive marketing is done on the continents of Asia and Africa, where cigarettes are marketed in television, radio and print advertising, at schools, sports and music events, and even more subtly, in the form of sponsorship at charitable events. Still, there are thousands of organizations working to ban smoking, educate youth and adults about smoking and health related issues, like lung cancer, emphysema, heart disease among other diseases.

What Lung Cancer Does To Your Body
While all the advertising inundates the public with images of how "sexy" smoking is supposed to be, what they don't show is the ugly side of smoking, how it stains, erodes and damages your teeth, taste buds, throat, esophagus, lungs and inevitably, threatens your life. Granted, not everyone who smokes gets lung cancer and dies; however, it is proven that cigarettes do contribute to lung cancer.

Lung cancer occurs when cells start to grow uncontrollably in a random fashion, causing tumors in the bronchial tubes, mucous glands, and near the air sacs and surface of the lungs. These tumors grow rapidly into larger tumors and can eventually spread throughout the body and into the chest, bones, spine or other organs. The more rampant the cancer in a body, the higher chance one has of multiple tumors, organ failure; and, a lesser chance for survival.

Lung Cancer Prevention/Detection/Screening/Treatment
One can take several steps to prevent the occurrence of lung cancer. First, if you are a non-smoker, promise yourself that you will never pick up a cigarette. Secondly, avoid inhaling second-hand smoke. Also, since lung cancer can also be caused by toxins in the environment, like radon gas and asbestos, it is important to be aware of their existence, and to avoid exposure.

For people who have a history of lung cancer in their families, lung cancer can be detected by screening via x-rays, CT scans, biopsies, testing of coughed up mucus, and blood tests. Lung cancer, in its early stages has no noticeable symptoms; however, as it progresses, lumps, coughing, blood-stained phlegm, breathlessness, chest pain, recurrent pneumonia or bronchitis, weight loss and fatigue can occur.

According to lungcancer.org, there is currently no approved screening test for lung cancer that has been proven to improve survival or detect localized disease. However, there are many studies under way to find an appropriate screening tool. If detected early, lung cancer can be treated, depending on the type and extent of the cancer. In instances where the cancer is localized in the lung, surgery can remove the tumors. When the cancer has spread beyond the chest, chemotherapy and radiation are used as treatment. Some patients can even elect to have lung transplants, where the diseased lung is replaced by a healthy one.

Resources/Initiatives
For those trying to quit, the good news is that there are a myriad of resources, nationally and internationally, to help people quit. International agencies like the Environmental Protection Agency (EPA) and the World Health Organization (WHO) have extensive data and resources on their websites to educate the public about the dangers of smoking. In 1998, WHO established the Tobacco Free Initiative (TFI), which is dedicated to framing global tobacco policy and focusing international resources on the global tobacco epidemic.

The American Cancer Society, the National Cancer Institute, and lungcancer.org are among the many organizations that provide information, education and resources to help smokers quit. There are telephone, on-line, group and one-on-one support groups, government and community funded that provide counseling. Some people use and therapy, various medications, including the patch, hypnosis and nicotine pills to assist them in quitting.

One of the most important factors in quitting and sticking to it is having a strong support system. If you are trying to quit or help someone to quit, keep in mind that cigarette smoking is extremely addictive and that people trying to quit can experience anxiety, depression and irritability, as they crave the nicotine their body has become accustomed to ingesting. Because of how addictive nicotine is, some people give up quitting or experience relapses in smoking after only a short time. Thus, it is very important to get lots of support from family and friends, since they can provide reminders of the benefits to quitting.

Other Risks
Besides the risk of getting lung cancer, there are a multitude other health related illnesses that can develop due to smoking, including heart attack and stroke, blood pressure, respiratory diseases, cancer in other parts of the body and cardiovascular diseases. People who smoke also put others around them at risk. Women who smoke give birth to babies with lower birth rates, children of parents who smoke can develop respiratory illnesses and people who inhale second-hand smoke have a higher risk of developing lung cancer or other smoking-related disease. (National Cancer Institute).

Then, there is the economic downside to smoking. According to www.cancer.org, tobacco creates "...hugely increased healthcare costs...diversion of agricultural land that could grow food, the costs of fires and damage to buildings caused by careless smokers, the resulting increase in insurance premiums, employee absenteeism, decrease in worker productivity...widespread environmental costs due to large-scale deforestation...pollution, and the millions of discarded butts and cigarette packaging that litter streets and waterways (www.cancer.org)."

In the USA, between 1997 and 2001, tobacco smoking resulted in $92 billion of annual productivity losses; worldwide, smoking accounted for 10% of fire deaths, the total [number of people] killed by fires caused by smoking [was] 300,000 and the total cost of fires caused by smoking was $27 billion. In 2003, cigarette litter accounted for 34% of the trash collected along the world's coasts; every year, children start 1,000,000 fires using lighters, and as of 2005, the economic costs to the economy healthcare included was upwards of $300 billion dollars (www.cancer.org).

Benefits of Not Smoking
On the upside, there are a myriad of benefits to quitting smoking. You can prevent health related illnesses like emphysema, heart disease and lung cancer by never smoking or quitting smoking as soon as possible. Quitting as soon as possible can improve the quality and longevity of your life. According to the National Cancer Institute, there are almost instant health improvements when a person quits smoking. "Within just a few days of quitting, a person's sense of taste and smell return, and breathing becomes easier; blood pressure, which becomes elevated while smoking, begins to return to normal. Research has shown that people who stop smoking before the age of 35 reduce their risk of developing a tobacco-related disease by 90%, but older smokers can also benefit greatly from quitting. Even smokers who quit after being diagnosed with a smoking-related illness reduce their risk of medical complications and of dying from a tobacco-related disease".

The key thing that I want to leave with you is this. Your life is in your hands - literally. You are in control. Smoking, as addictive as it may be, is a choice. Every time a smoker lights up a cigarette and inhales, that individual is making a conscious decision to harm his/her body; and every time the smoker exhales the cigarette smoke, he/she is harming others and the environment.


By Maimah Karmo

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